ABSTRACT
Objectives: To observe Quality of Life [QoL] in diabetes mellitus patients after fabrication of immediate dentures
Setting: Department of Prosthodontics in Hamdard University Dental Hospital, Karachi
Period: Two years from October 2011 to September 2013
Methodology: Thirty patients with established diagnoses of diabetes mellitus reported. In this study by purposive non-probability sampling technique. In this study patients were selected, male and female patients were 24 and 6 respectively with the age range of 22- 74 years. After getting consent Questions mention in OHIP-14 were asked from the patients on 1[st] visit and 2 months later after fabrication of immediate denture to assess the QoL of in these patients. Data was obtained after using SPSS-version 19. For analysis Wilcoxon Signed Ranks Test was applied to get results. Probability level of P
Results: There was marked improvement in different domains of QoL in diabetes mellitus patients after fabrication of immediate dentures, most of the patients were pleased with their prosthesis. Three patients had complained of pain on buccal side which was corrected by trimming the overextended flange of their denture. All patients had improvement in phonetics [P value 0.01], better choice of food [P value 0.00], eating ability [P value 0.01], decrease embarrassment [P value 0.08] and self-assurance [P value 0.025]. However, effect of immediate denture on variable like tension was not advantageous having P-value of 0.157
Conclusion: By fabrication of immediate dentures to diabetes mellitus patients, QoL can be markedly improved in such patients
ABSTRACT
Tumour-induced osteomalacia [TIO] is a rare paraneoplastic syndrome usually presenting with bone pain, fracture of bones and muscle weakness. It is caused by high serum levels of fibroblast growth factor 23 [FGF-23], which is a hormone-regulating phosphate, and vitamin D. FGF-23 is secreted by several tumours, especially benign mesenchymal tumours which are very small and difficult to locate. There is a significant delay from onset of symptoms to the diagnosis of this entity due to occult nature of this disease. We present a case of young male who presented with long history of progressively worsening muscular pain and weakness, rendering the patient confined to bed. Our aim of presenting this patient as a case report is to make physicians realise that any patient with unexplained muscular weakness and pain must undergo workup for TIO, including serum phosphate measurement, as this is a rare but potentially curable disease